until ≥7-14 days after clearance of the parasite). Ivermectin is also the preferred treatment for hyperinfection/disseminated strongyloidiasis, usually in prolonged courses (e.g. Strongyloides also causes disseminated disease (hyperinfection syndrome) in certain hosts. The preferred treatment for uncomplicated strongyloidiasis is oral ivermectin (200mcg/kg daily for 2 days), which cures 70-85% of chronically infected patients. Household and other close contacts should also be treated, and a second treatment dose is recommended 2 weeks after the first dose because of high re-infection rates and the frequent occurrence of autoinfection. Preliminary data suggest that mebendazole may be slightly superior to albendazole for whipworm and that combination therapy with ivermectin may be superior to albendazole or mebendazole monotherapy.įor hookworm, single-dose albendazole (400mg) is preferred over single-dose mebendazole (500mg).įor pinworm (Enterobius), single-dose therapy with albendazole (400mg) or mebendazole (100mg) is highly effective. For Trichuris infections, at least 3-7 days of albendazole (400mg BID) or mebendazole (100mg BID) should be used, because single-dose cure rates are low.
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